Endocrine Abstracts

Neuroendocrine tumors encompass a heterogeneous group of tumors arising from the diffuse neuroendocrine system. The incidence of NETs rises with age, with the peak after 65 years. However, all NETs observed in adults may be diagnosed in children too. There are a very few studies addressing NETs in young patients. This study summarizes clinical, histopatological and genetic characteristics of young patients with NETs. This is a retrospective study describing clinical, histopath...

Overconsumption of fructoseenriched beverages and everyday stress are both involved in the pathogenesis of metabolic disorders through their effects on hepatic lipid metabolism. The aim of this study was to investigate whether highfructose diet and chronic stress synergistically perturbs lipid metabolism in rat liver. Therefore, we analyzed the effects of 9-week 20% liquid fructose diet and 4-week chronic unpredictable stress, separately and in combination, on dyslipidemia, VL...

Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a rare multitumour syndrome, characterized by the occurrence of parathyroid (PHPT), pituitary adenoma (PA) and pancreatic neuroendocrine tumors (pNETs). The gene responsible is MEN1 gene, however 10 to 20% of patients are not carriers of MEN1 mutation. Recently, a study has shown that these patients have less aggressive course of the disease, and more favorable life expectancy than their mutation-pos...